Unlike real life, you cannot "upload" a .ino file directly into Proteus. You must simulate the compiled hex file.
Enable users to easily download, install, and use Arduino-specific libraries ( .IDX , .LIB ) within for simulation of Arduino boards (Uno, Mega, Nano, etc.). proteus arduino library download
A student wants to simulate an LED blink with Arduino Uno in Proteus. Uses the feature to download & install the Arduino Uno library, then places the board, loads blink.hex , and runs the simulation without hardware. Unlike real life, you cannot "upload" a