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: Operates as a menu-driven program within Excel, allowing users to select data ranges via simple drag-and-drop.
It is completely free for academic and research use.
: It helps eliminate human errors in manual formula entry. However, one study noted that results for certain parameters (like the release exponent ' ddsolver.xla
For drugs that release at a constant rate regardless of concentration.
Often used for drugs released from matrix systems.
The tool allows users to fit their experimental data to several mathematical models to determine the mechanism of drug release: Yong Zhang, Meijia Huo, Jianping Zhou, Shengjun Zou,
The file extension .xla indicates an . Specifically, ddsolver.xla is the filename for the Solver Add-in in older versions of Microsoft Excel (typically Excel 97 through 2003, though it can still be present in newer versions for compatibility).
The add-in automatically generates tables and charts, including the correlation coefficient ( R2cap R squared
Input your dissolution time points and the corresponding percentage of drug released into a standard Excel sheet. However, one study noted that results for certain
using established mathematical equations.
when comparing models. The model with the highest value usually indicates the most accurate description of your drug's release mechanism. Real-World Applications
