(Robin Tunney): A lawyer and Lincoln's ex-girlfriend who works on the outside to prove his innocence .
(Wade Williams): The sadistic Captain of the guards at Fox River who later finds himself on the other side of the bars. 🏥 Supporting Allies Dr. Sara Tancredi
(Sarah Wayne Callies): The prison doctor and Michael’s primary love interest who plays a crucial role in the escape and conspiracy . Veronica Donovan who is in prison break
(Lane Garrison): A young pickpocket caught between the inmates and the guards. Charles "Haywire" Patoshik
Michael's brother, who is wrongfully convicted of murdering the Vice President's brother and sentenced to death row. Key Allies and Inmates (Robin Tunney): A lawyer and Lincoln's ex-girlfriend who
(Silas Weir Mitchell): Michael's second cellmate who has a neurological disorder and becomes obsessed with Michael’s tattoos . 🛡️ Law Enforcement & Antagonists
( Wentworth Miller ): A structural engineer who gets himself incarcerated to break his brother out. He is famous for his full-body tattoo containing the prison blueprints. Lincoln Burrows Sara Tancredi (Sarah Wayne Callies): The prison doctor
At the heart of every season are the two brothers who appear in every episode of the series.
The brothers are pursued by various government agents and prison officials throughout the seasons. Alexander Mahone