The battle specifically takes place between and Episode 169 .

The fight takes place during the "Pain's Assault" arc (also known as the "Two Saviours" arc), which covers episodes 152 to 175. While the broader invasion begins earlier, Naruto's direct confrontation with the Six Paths of Pain is the centerpiece of the following key episodes:

Naruto defeats the final Path of Pain (the Deva Path) and tracks down the real body, Nagato.

To wrap things up, if you want to jump straight into the fight:

This episode features Naruto losing control and transforming into his six-tailed (and eventually eight-tailed) state. It is famous for its unique and experimental animation style.

The legendary battle between Naruto Uzumaki and Pain occurs in of Naruto Shippuden . The primary confrontation begins in Episode 163 , titled " Explosion! Sage Mode ," and concludes in Episode 169 , titled " The Two Students ". Quick Episode Guide: Naruto vs. Pain